brain food, brain nutrition, food as medicine, nutritional healing, functional medicine,

Brain Food: Feed, Heal, and Protect Your Brain

Brain Food: We can eat our way to better brains–and protect the vibrant minds we cherish–regardless of a devastating family history like mine.

I am especially concerned about my brain as I age. My Dad started showing signs of cognitive decline in his 60s and was diagnosed with Parkinson’s disease with rapidly progressive dementia in his 70s. We’ve watched his deterioration with horror. He currently lives in a skilled nursing facility where he receives twenty-four hour care for all aspects of his life. There are days when he sleeps and hardly knows his wife when she comes for their daily visit, and occasions when he’s more lucid and enjoys life’s simple pleasures. But he’s no longer the man he was.

My dad is the second consecutive generation to suffer this fate–my Grandpa also had Parkinson’s disease and dementia, finally dying from heart failure in his 70s. This family legacy has my rapt attention. What’s in store for me?

Fortunately, there are two revolutionary innovations in scientific thought with real life applications that give me hope and practical solutions: Epigenetics and Neuroplasticity.

The science of Epigenetics shows us that we literally change our gene expression–and thus our biology–when we change our environment. We are not destined to the same fate as our ancestors. While we may share the same genes, those genes leave very distinctive signatures–with different health outcomes–determined by the contrasting ways in which we live our lives.

Neuroplasticity is the promise that our brains can heal. With the right conditions in place, our brains repair, form new connections, grow, and improve function. We can both prevent and recover from all manner of brain injury and dysfunction.

The food we eat has undoubtedly the greatest influence on what our genes are up to, and is the major power player in the health of our brains.

We can change the direction of our destinies–by harnessing the power of food–Brain Food–to feed, heal, and protect our brains.

What’s Brain Food?

Brain Food feeds our minds, supporting the cognitive performance we depend on to thrive and enjoy our lives. Robust nutrition supports our brain’s ability to create energy, repair itself, and maintain healthy structure and function. What it’s not are those foods that are toxic or irritating, leading to damage and distress in our brains.

Brain Food Attributes (we can do ALL this with the food we eat!)

  • Provides essential nutrients required for healthy structure, function, and repair.
    • Healthy Fats
    • Healthy Proteins
    • Micronutrients
    • Antioxidants
  • Downshifts excesses of damaging inflammation.
  • Enhances detoxification and clearance of toxic substances from the brain.
  • Improves energy production in the brain.
  • Maintains healthy blood sugar levels and improves insulin sensitivity.
  • Increases ketone levels (products of using fat to make energy).
  • Supports a healthy gut and microbiome–leading to a healthier brain via the Gut-Brain Connection.
  • Helps optimize hormone balance (energy, stress, and sex hormones).
  • Supports production of Brain-Derived Neurotropic Factor (BDNF), a powerful molecule that protects the brain.
  • Supports Nuclear Receptor Factor 2 (NrF2) to enhance the production of glutathione (powerful brain antioxidant and detoxicant).
  • Supports Nuclear Factor Kappa Beta (NFKB) to put the brakes on inflammation.
  • Increases levels of Glutathione and other important brain anti0xidants.

Ideal Brain Food Plan for Protection and Enhancement of Brain Health

The ideal way to eat for brain protection and rehabilitation is to follow a very low carbohydrate, nutrient-dense, anti-inflammatory food plan. This is easily accomplished by keeping intake of healthy fats high, carbohydrates low (with no sugar, grains, or highly processed carbohydrates), and by following the guidelines below for foods to exclude and top Brain Foods to include in your plan. Eating this way will shift your metabolism toward using fats to make energy, away from sugar, creating conditions highly favorable for brain health and cognitive performance.

The ideal Brain Food plan will also provide all key brain nutrients, while avoiding inflammation promoting foods.

No-Brainer Foods to Exclude

Forgive the pun, but these are the foods that are not good for the brain.

Those of you who know me or who utilize a Functional Medicine approach to lifestyle and healing, know that these are the most problematic foods we eat by driving inflammation, toxicity, and blood sugar imbalances–conditions that damage the brain.

  • All grains
  • Animal milk products
  • All sugars
  • All processed foods (with the exception of high quality supplements or protein powders)
  • High mercury fish (tuna, shark, swordfish)
  • High sugar-content fruit
  • Beans and legumes
  • All meat or eggs derived from industrial farms (stick to 100% pasture-raised, grass-fed animals)
  • All food contaminated by pesticides or herbicides (glyphosate)
  • Reduce alcohol–limit to 5 ounces wine or beer per night, taken with or after evening meal.

For those who have suffered from inflammatory or autoimmune disorders, or upon recommendation from your trusted healthcare practitioner (preferably trained in Functional Medicine), you may also need to reduce intake of (or completely eliminate) eggs, nuts, and nightshade vegetables (tomatoes, white potato, sweet and hot pepper, egg plant).

Top Brain Foods

Healthy Fats

  • Omega-3 Fats from wild-caught fish: salmon, mackerel, anchovies, sardines, herring.
  • MCT oil: medium-chain triglycerides derived from organic coconuts–help drive ketosis and support brain energy production.
  • Coconut fat: coconut milk (culinary version, not from carton), coconut cream, butter, fresh, oil.
  • Avocados

Healthy Protein

  • Enough wild-caught fish (see above), or pasture-raised beef or chicken to meet protein requirements.
  • Pasture-raised eggs.
  • Average protein need is 0.5 to 0.8 grams protein per pound body weight consumed over a day.

Low Starch-High Nutrient Vegetables

  • Mushrooms
  • Cruciferous vegetables
  • Dark green leafy vegetables
  • Sulfur-containing vegetables: onion, garlic, cabbage

Low Sugar-High Nutrient Fruit

  • Blueberries
  • Blackberries
  • Pomegranate seeds
  • Cranberries

Probiotic and Prebiotic Vegetables

  • Probiotic foods: sauerkraut, kimchi, kambucha
  • Prebiotic foods: resistant starches (sweet potato, rutabaga, parsnips), jicama, leeks, artichokes


  • Coffee
  • Black tea
  • Green tea
  • Golden milk (coconut milk, ginger, turmeric, black pepper)

Spices and Condiments

Brain Food Supplements

  • Turmeric Extract–also called Curcumin: powerful anti-inflammatory; take 2-3 grams per day in divided doses of product standardized to at least 90% curcuminoids.
  • Resveratrol: take 1-2 100 mg capsules twice daily.
  • Fish oil: EPA and DHA are the major omega-3-fatty acids from fish–take 1-2 grams of each daily in divided doses, with a fatty meal to improve absorption.
  • Vitamin D: 5-10,000 IU per day taken with a fatty meal; ask your doctor for 25-hydroxy vitamin D levels–the goal is to be in the range of 70-80.
  • Glutathione: master brain anti-oxidant/detoxicant–take 300-400 mg per day in a liposomal form.
  • NAC–N-acetyl cysteine: the precursor for Glutathione–take 400-600 mg per day.
  • MCT oil–medium chained triglycerides: take 1 tablespoon 1-2 times daily, first dose in the morning (I put it in my tea).


Karyn Shanks, MD. The Gut-Brain Connection: Root Cause Solutions for Depression. 2017.

Karyn Shanks, MD. Gut-Brain Connection–Part Two: Action Steps for Healing Depression. 2017.

Karyn Shanks, MD. Intermittent Fasting: How it Energizes My True Life. 2017.

Karyn Shanks, MD. Healing Foods: My Favorite Healthy Fats. 2016.

Karyn Shanks, MD. Protein: How Much Do We Need to Support Optimal Health? 2016.

Karyn Shanks MD


Karyn Shanks, MD, is a physician who lives and practices in Iowa City. Her work is inspired by the revolutionary science of Functional Medicine, body-mind wisdom, and the transformational journeys of thousands of clients over her twenty-eight year career. She believes that the bones of healing are in what we do for ourselves.


    Hi Karyn, I’m sorry to hear about your dad. When we were growing up, I remember Bob as a vital, intelligent, healthy guy.

    Sadly, people of his generation had virtually no exposure to the type of nutritional information contained in your posting today.

    Back in the days, lone voices like Jack Lalanne, Euell Gibbons and Jay Kordich were disconnected and considered eccentric at best.

    Today, thanks to Drs. Mercola, Mark Hyman and Daniel Amen, there is a cohesive, data driven and irrefutable message about the importance of diet, exercise and nutrition in long term vitality.

    Sadly, the medical community is not only ignorant but outright defiant to this overwhelming scientific evidence.

    It’s now incumbent upon enlightened grass roots practioners like you to unite via the blogoshphere to quash the medical system that remains deeply in the pockets of big pharma.

    The irony? While we now have a wealth of information, our modern lifestyle virtually prohibits incorporating new, unfamiliar habits.

    The trick is to develop a system that each individual can gradually build into a daily routine.


    Thanks for your note, Paul… Working on that “squashing,” though in a positive way–by putting the information in the hands of the people who need it. Oh, and good news–Functional Medicine and integrative/lifestyle/nutritional approaches to healing are on the rise. It’s here. And it will prevail. Nothing else works.


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